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National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Účinek mutací v adipokinetickém hormonu a corazoninovém receptoru na metabolismus sacharidů a lipidů u \kur{D. melanogaster}
 SVOBODOVÁ, Karolína
In D. melanogaster, metabolic homeostasis is regulated by an interplay between insulin-like peptides and glucagon-like neuropeptides. Here we examined the influence of corazonin receptor (CrzR) mutations on levels of circulating saccharides, circulating lipids and starvation resistance. We also verified the interaction between null mutations of corazonin receptor and adipokinetic hormone and checked their influence on insulin signaling.
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Vliv adipokinetického hormonu na působení jedu z vosičky, \kur{Habrobracon hebetor}, ve svalové tkáni octomilky, \kur{Drosophila melanogaster}
 PODLAHOVÁ, Šárka
Adipokinetic hormone (AKH) delays or reduces neuromuscular paralysis caused by the venom of the parasitic wasp Habrobracon hebetor, however the associated mechanism is not known yet. This thesis describes in detail the technique of preparation of semithin and ultrathin sections analyzed by a transmission electron microscopy that enabled detailed observation of changes in muscular ultrastructure of the Drosophila melanogaster thorax after the wasp venom and AKH treatments. The results revealed that the wasp venom induced significant changes in the ultrastructure of myofibrils and mitochondria; however, the changes were reduced after co-application with AKH. AKH itself did not affect organization of muscle fibres but elicited vacuolization in mitochondria. Furthermore the wasp venom treatment led to significant prolongation of sarcomeres.
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